00054007979005

description

• Recommended for secondary polishing cell clarification applications, such as DNA removal, in recombinant proteins, such as monoclonal antibodies, 3M™ Zeta Plus™ EXT Series Filter Cartridge with ZB Series Media minimizes hold-up volume and maximize product recovery, while providing a particle free permeate solution for downstream processing.

features

• Suitable for primary cell culture filtration or intermediate polishing applications in R&D, Process Development or manufacturing of recombinant protein drugs such as monoclonal antibodies
• Made using cellulose fibers, diatomaceous earth and a binding resin that imparts a positive charge (quaternary amine), ZB grade media filters particles from process solutions through mechanical sieving and electrokinetic adsorption mechanisms
• Wide range of filter pore sizes (0.1 to 4 µm) and a dual layer lenticular construction allows for optimizing filter throughput and filtrate quality
• Scaleable single use filter portfolio enables using the same filtration platform process liquids volumes of 0.5 to 20,000 liters
• Unique filter capsule design minimizes hold-up volume and maximizes product recovery, while reducing the need for cleaning validation
• translucent plastic shell allows easy detection of the liquid level for real time monitoring of the filtration process and to minimize flush volumes
• Cam-lock connections on Zeta Plus Encapsulated capsules, and holder design allows for easy assembly and tear down of filtration system and improving productivity of manufacturing clean room